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. 2021 Sep 7;12:704044. doi: 10.3389/fphys.2021.704044

FIGURE 3.

FIGURE 3

Moderate sepsis modulates fiber profile. mRNA expression of Myh4 (encodes MHC IIb expressed in fast-glycolytic type II fiber; A), Myh7 (encodes MHC I expressed in slow-oxidative type I fiber; B), Atp2a1 (encodes SERCA1 expressed in fast-glycolytic type II fiber; C), and Atp2a2 (encodes SERCA2 expressed in slow-oxidative type I fiber; D) in the diaphragm. Western blot representative figure for measuring MyHC I (fiber type I marker), MyHC IIa (fiber type IIa marker), and MyHC IIb (fiber type IIb marker; E). Relative protein expression of MyHC I (F), MyHC IIa (G), and MyHC IIb (H). Black dots represent sham animals caused by surgical stress, and gray squares represent CLP – cecal ligation puncture technique. Values are expressed as mean ± SD, *p < 0.05, and **p < 0.005 compared with the sham group.