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. 2021 Sep 7;9:727356. doi: 10.3389/fchem.2021.727356

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Copyright © 2021 Cao, Li, Yang, Yao, Wang, Yu, Shen, Yao and Wu.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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(A) Fluorescent images of MC3T3-E1 cells on different surfaces (blue: nucleus, red: cytoskeleton). Spindle-shaped cells were indicated by gold arrows and lamellipodia were indicated by green arrows; Statistics of relative cell areas (B) and lamellipodia areas (C) according to the fluorescent images, Mg group was taken as a control group, (data displayed as mean ± standard deviation, *p < 0.05, **p < 0.01.) (n = 6).