Table 4.
Association results of wb-mtDNA levels with 28-day survival in ARDS patients adjusting the models for the variables that were significantly different by mortality group.
| N | Hazard ratio (95% CI) | p-value | |
|---|---|---|---|
| wb-mtDNA levels | 264 | 3.65 (1.39–9.59) | 0.009 |
| Adjusted by age | 264 | 3.99 (1.46–10.87) | 0.007 |
| Adjusted by SAPS | 131 | 7.93 (1.57–39.93) | 0.012 |
| Adjusted by APACHE II score | 258 | 4.26 (1.56–11.64) | 0.005 |
| Adjusted by organ dysfunction: | |||
| Neurological systems | 263 | 3.48 (1.30–9.27) | 0.013 |
| Coagulation | 264 | 3.93 (1.47–10.42) | 0.006 |
| Hepatic | 264 | 3.66 (1.39–9.62) | 0.009 |
| Renal | 264 | 3.85 (1.46–10.20) | 0.007 |
| Adjusted by days in hospital* | 228 | 5.77 (1.70–19.53) | 0.005 |
| Adjusted by days in ICU* | 264 | 4.64 (1.67–12.87) | 0.003 |
| Adjusted by age, APACHE II | 258 | 4.51 (1.62–12.57) | 0.004 |
| Adjusted by age, APACHE II, organ dysfunction | 257 | 4.40 (1.55–12–53) | 0.006 |
*Statistically significant for the Schoenfeld test of the proportionality of risks.
APACHE II, Acute Physiology and Chronic Health Evaluation II; ICU, intensive care unit; SAPS, Simplified Acute Physiology Score II.