Table 2:

Animal models of asthma pertinent to PTSD-relevant behaviors

Model	Behavior	Immune Response	Citations
Ovalbumin (non-CNS, non-self antigen)	↑ Anxiety ↓ Spatial learning ↑Fear Response	Antibodies: IgE IgG1 T-cell: Th2 cyokines, IL-17, Treg TNFα	Costa-Pinto et al., 2005 Bei et al., 2013 Tonelli et al., 2009 Dehdar et al., 2019 Zuo et al., 2014
House Dust Mite	↑ Anxiety ↑ Anhedonia ↑ Extinction Freezing	Cortisol Th2 cytokines: IL-4, IL-5, IL-13	Caulfield et al., 2017 Caulfield et al., 2018 Lewkowich et al., 2020