Table 3:

Associations of percent density (PD) measures with breast cancer and case-control discriminatory performance on ds5, using logistic regression models adjusted for age and BMI. P-values for both AUCs and ORs were obtained from 1,000 bootstrap samples to test for the null hypothesis of no difference from the AUC or OR derived from Deep-LIBRA using the same breast views.

Density score	OR (95% CI)	p-value	AUC (95% CI)	p-value
Deep-LIBRA PD (4 views)	1.61 (1.37,1.88)	-	0.612 (0.584, 0.640)	-
Deep-LIBRA PD (CC)	1.64(1.40,1.91)	-	0.611 (0.583, 0.639)	-
Deep-LIBRA PD (MLO)	1.46(1.26,1.69)	-	0.596 (0.568, 0.624)	-
Cumulus PD (CC)	1.64(1.39,1.93)	0.99	0.619 (0.592, 0.647)	0.85
LIBRA PD (4 views)	1.26(1.09,1.46)	<.001	0.564 (0.535, 0.592)	0.01
LIBRA PD (CC)	1.19 (1.04,1.36)	<.001	0.557 (0.528, 0.585)	0.01
LIBRA PD (MLO)	1.26(1.10,1.46)	0.07	0.561 (0.533, 0.589)	0.04
Volumetric Volpara PD (4 views)	1.55 (1.31,1.82)	0.43	0.599 (0.572, 0.627)	0.37
Volumetric Volpara PD (CC)	1.45 (1.24,1.71)	0.02	0.588 (0.559, 0.616)	0.09
Volumetric Volpara PD (MLO)	1.62(1.37,1.92)	0.10	0.598 (0.570, 0.626)	0.88
Area Volpara PD (4 views)	1.48 (1.25,1.74)	0.10	0.578 (0.551, 0.607)	0.04
Area Volpara PD (CC)	1.38 (1.18,1.61)	<.001	0.567 (0.539, 0.596)	0.01
Area Volpara PD (MLO)	1.62(1.28,1.79)	0.53	0.591 (0.563, 0.619)	0.49
BI-RADS density	1.54(1.30,1.81)	0.45	0.596 (0.568, 0.624)	0.35