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Comparison of latex agglutination test and PCR gene amplification for the detection of S. pneumoniae in TNA samples from patients with moderate-to-severe CAP
| Parametera | Latex agglutination
|
PCR
|
||
|---|---|---|---|---|
| Strict criteria | Expanded criteria | Strict criteria | Expanded criteria | |
| Sensitivity (%) | 52.2 | 53.6 | 91.3 | 89.7 |
| Specificity (%) | 88.7 | 93.0 | 83.3 | 90.0 |
| PPV (%) | 63.2 | 78.9 | 65.6 | 81.3 |
| NPV (%) | 83.3 | 80.3 | 96.5 | 94.7 |
PPV, positive predictive value; NPV, negative predictive value.
