TABLE 5.

Patients with a final diagnosis of pneumococcal pneumonia who had received previous antibiotic therapy

Patient no.	Previous antibiotic therapy	TNA			Sputum Gram stainb	Other positive cultures for S. pneumoniae
		Culture	LAa	PCR
17	Ciprofloxacin	+	ND	+	ND	No
18	Amoxicillin-clavulanated	+	−	+	ND	No
19	Norfloxacin	−	−	+	SR	Blood
20	Ciprofloxacin	−	−	+	GPDC	Pericardial fluid
9c	Ciprofloxacin	−	ND	+	GPDC	No
6c	Roxithromycin	−	+	−	GPDC	No

^aLA, latex agglutination; ND, not done. 

^bSR, specimen rejected (because of poor quality); GPDC, gram-positive diplococci. 

^cCases considered to be pneumococcal pneumonia by the expanded criteria (they are also listed in Table 4 with the corresponding numbers). 

^dMIC of amoxicillin = 4 μg/ml.