Skip to main content
. Author manuscript; available in PMC: 2022 Oct 1.
Published in final edited form as: Brain Behav Immun. 2021 Jul 2;97:79–88. doi: 10.1016/j.bbi.2021.06.018

Table 5.

Adult Stressful Life Events (from age 21 to 26 and age 32 through 44) and suPAR at age 45 Moderated by ACEs

Outcome: suPAR at age 45
N = 828 β 95% CI p β 95% CI p
Prospective ACEs 0.16 [0.09, 0.23] < .001 0.09 [0.02, 0.15] .008
Adult stressful life events 0.17 [0.11, 0.24] < .001 0.11 [0.04, 0.17] .001
Prospective ACEs × Adult Stressful Life Events 0.13 [0.06, 0.19] < .001 0.10 [0.04, 0.17] .001
Sex −0.16 [−0.22, −0.09] < .001
Smoking at 45 0.27 [0.21, 0.34] < .001
BMI at 45 0.13 [0.06, 0.19] < .001
Anti-inflammatory medication use at 45 0.05 [−0.01, 0.12] .085

Note: Stressful life events in adulthood included stressful life events from age 21 to 26, 32 to 37, and 38 to 44. ACEs = adverse childhood experiences; BMI = body mass index; suPAR = soluble urokinase plasminogen activator receptor.