Table 1.
Dissociation constants for lipids and IPs binding to HTLV-1 myr(−)MA obtained by plotting CSPs vs. lipid concentration.
| Lipid | Kd (μM) |
|---|---|
| diC4-PI(4,5)P2 (0 M NaCl) | 7.2 ± 2.1 |
| diC4-PI(4,5)P2 | 306 ± 30 |
| diC6-PI(4,5)P2 | 195 ± 19 |
| I(1,4,5) P3 | 338 ± 42 |
| I(1,4,5)P3 (0 M NaCl) | 4.0 ± 1.3 |
| I(1,3,4,5)P4 | 62 ± 14 |
| IP6 | 23 ± 11 |
| IP6 (0.2 M NaCl) | 36 ± 7 |
| IP6 (0.4 M NaCl) | 295 ± 56 |
Titrations were conducted in the presence of 0.1 M NaCl except when noted. Kds are average values obtained from plotting CSPs of 3-4 NMR signals.