The expression and activity of JAK2 and STAT3 in pancreatic tissues of SAP rats. (A) The protein level of p-JAK2, JAK2, p-STAT3, STAT3 and GAPDH in rat pancreases were determined by western blotting. (B) The quantitative analysis result of p-JAK2/JAK2 ratio. n = 8–11. (C) The quantitative analysis result of p-STAT3/STAT3 ratio. n = 8–11, all data are expressed as mean ± SD. *P < 0.05, **P < 0.01 vs Control. #P < 0.05 vs SAP+5% DMSO, unpaired two-tailed t-test. SAP: severe acute pancreatitis.