Fig. 2.

JAK2 inhibition protects against SAP-induced pancreatic damage and inflammation. (A) Representative H&E staining photos of pancreases showing JAK2 inhibitor AG-490 reduced tissue edema (Green arrows) and inflammation (Red arrows). (B) Summarized pancreatic histological score showing the beneficial effect of AG-490 on pancreatic homeostasis. n = 8–11, all data are expressed as mean ± SD. **P < 0.01 vs Control. ^##P < 0.01 vs SAP+5% DMSO, unpaired two-tailed t-test. (For interpretation of the references to colour in this figure legend, the reader is referred to the Web version of this article.)