Table 10.

Associations between DBP exposure (measured by MBP) and motor effects.

Reference; study confidence; N	Age at outcome measure	Median maternal exposures	Exposure IQR (or as specified)	Motor overall effect estimate β (95% CI)	Motor in boys β (95% CI)	Motor in girls β (95% CI)
Polanska et al.(2014); medium; 150	2 yr	4 ng/mL	130 (95^th)	−1.2 (−2.5, 0.1)	NR	NR
Kim et al. (2011); medium; 460	6 mo	17 ng/mL	5.4‒41.1	−0.8 (−1.6, 0.03)	−1.3 (−2.4,−0.1)	−0.4 (−1.6,0.8)
Gascon et al. (2015); high; 367	1 yr	31 μg/g	20‒49	0.7 (−1.5,3.0)^{^}	1.8 (−1.7,5.3)^{^}	0.6 (−2.6,3.7)^{^}
Gascon et al. (2015); high; 367	4 yr	31 μg/g	20‒49	−0.4 (−2.4,1.6)^{^}	0.2 (−3.3,3.6)^{^}	0.2 (−2.3,2.6)^{^}
Doherty et al. (2017); medium; 258	1–3 yr	35 ng/mL	202 (95^th)	0.6 (−0.8,1.9)	1.9 (0.3,3.5)	−2.3 (−4.6,0.1)
Whyatt et al. (2012); medium; 319; Balalian et al. (2019); 209	3 yr	37 ng/mL	19–75	−2.8 (−4.6, −1.0)^*	−3.1 (−5.8,−0.3)^*	−2.4 (−4.9,0.1)
	11 yr	37 ng/mL	19–75	NR	−0.6 (−2.0,0.7)	−2.1 (−3.4,−0.8)^*
Tellez-Rojo et al. (2013); medium; 135	2–3 yr	86 ng/mL (GM)	NR	0.5 (−0.7, 1.6)	0.9 (−0.5,2.3)	0.5 (−1.7,2.7)

One low confidence study (Kim et al., 2018) not shown in table because results were incompletely reported.

All studies used ln-transformed exposure and βs represent 1 ln-unit increase, except for Gascon, which used log2-transformation and β represent doubling of exposure.

Results that support an adverse association are shaded. This represents one or more of the following: p < 0.05, β ≥ 0.5, or exposure-response

trend across categories of exposure. NR = not reported. GM = geometric mean.

p < 0.05.

^{^}

Upon request, author provided re-calculated results with ln-transformed exposure and β representing a ln-unit increase, to improve comparability with other studies.