Table 11.

Associations between DIBP exposure (measured by MIBP) and motor effects.

Reference; study confidence; N	Age at outcome measure	Median maternal exposure	Exposure IQR (or as specified)	Motor overall effect estimate β(95% CI)	Motor in boys β(95% CI)	Motor in girls β(95% CI)
Téllez-Rojo et al. (2013); medium; 135	2‒3 yr	2 ng/mL (GM)	NR	0.6 (−0.7, 1.8)	0.6 (−0.7,2.0)	0.4 (−1.7,2.4)
Doherty et al. (2017); medium; 258	1–3 yr	6 ng/mL	35 (95^th)	0.1 (−1.3,1.6)	0.7 (−1.2,2.6)	−0.7 (−2.9,1.6)
Whyatt et al. (2012); medium; 319 Balalian et al. (2019); 209	3 yr	8 ng/mL	4–16	−2.3 (−3.9, 0.7)^*	−2.2 (−4.6,0.2)	−2.3 (−4.6, −0.1)^*
	11 yr	8 ng/mL	4–16	NR	−0.6 (−1.9,0.8)	−1.4 (−2.5,−0.2)^*
Polanska et al. (2014); medium; 150	2 yr	10 ng/mL	359 (95^th)	−0.6 (−1.3, 0.2)	NR	NR
Gascon et al. (2015); high; 367	1 yr	32 μg/g	22–48	−1.0 (−3.3,1.3)^{^}	−0.8 (−3.9,2.4)^{^}	−0.9 (−4.4,2.7)^{^}
Gascon et al. (2015); high; 367	4 yr	32 μg/g	22–48	−2.0 (−4.1,0.1)^{^}	−2.0 (−5.1,1.1)^{^}	−1.8 (−4.6,1.0)^{^}

One low confidence study (Kim et al., 2018) not shown in table because results were incompletely reported.

All studies used ln-transformed exposure and βs represent 1 ln-unit increase, except for Gascon, which used log2-transformation and β represent doubling of exposure.

Results that support an adverse association are shaded. This represents one or more of the following: p < 0.05, β ≥ 0.5, or exposure-response trend across categories of exposure. Light grey represents other supportive results. NR = not reported.

p < 0.05.

^{^}

Upon request, author provided re-calculated results with ln-transformed exposure and β representing a ln-unit increase, to improve comparability with other studies.