Table 12.

Associations between BBP exposure (measured by MBzP) and motor skills.

Reference; study confidence; N	Age at outcome measure	Median maternal exposure	Exposure IQR (or as specified)	Motor overall effect estimate β(95% CI)	Motor in boys β(95% CI)	Motor in girls β(95% CI)
Polanska et al. (2014); medium; 150	2 yr	0.03 ng/mL	0.5 (95^th)	−0.4 (−2.1, 1.3)	NR	NR
Téllez-Rojo et al. (2013); medium; 135	2–3 yr	4 ng/Ml (GM)	NR	0.1 (−1.2, 1.4)	1.8 (0.1,3.5)^*	−1.2 (−3.3,0.9)
Gascon et al. (2015); high 367	1 yr	12 μg/g	7–20	−0.8 (−2.8,1.3)^{^}	1.3 (−1.5,4.2)^{^}	−2.8 (−6.0,0.5)^{^}
Gascon et al. (2015); high 367	4 yr	12 μg/g	7–20	−2.2 (−4.0,−0.3)^{^}^*	−1.4 (−4.2,1.3)^{^}	−2.8 (−5.4,−0.2)^{^}^*
Whyatt et al. (2012); medium; 319 Balalian et al. (2019); 209	3 yr	13 ng/mL	5–27	−0.9 (−2.2,0.4)	−0.6 (−2.7,1.6)	−1.1 (−2.8,0.7)
	11 yr	13 ng/mL	5–27	NR	−0.9 (−1.8,0.1)	−1.1 (−2.1,−0.1)^*
Doherty et al. (2017); medium; 258	1–3 yr	15 ng/mL	124(95^th)	−0.6 (−1.8,0.6)	0.6 (−1.2,2.3)	−2.1 (−3.8,−0.4)

All studies used ln-transformed exposure and βs represent 1 ln-unit increase, except for Gascon, which used log2-transformation and β represent doubling of exposure. Results that support an adverse association are shaded. This represents one or more of the following: p < 0.05, β ≥ 0.5, or exposure-response trend across categories of exposure. NR = not reported. GM = geometric mean.

p < 0.05.

^{^}

Upon request, author provided re-calculated results with ln-transformed exposure and β representing a ln-unit increase, to improve comparability with other studies.