Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2020 Feb 3;75(5):1228–1236. doi: 10.1093/jac/dkz563

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2020. Published by Oxford University Press on behalf of the British Society for Antimicrobial Chemotherapy. All rights reserved. For permissions, please email: journals.permissions@oup.com.

This article is published and distributed under the terms of the Oxford University Press, Standard Journals Publication Model (https://academic.oup.com/journals/pages/open_access/funder_policies/chorus/standard_publication_model)

PMC Copyright notice

Figure 3. — Histopathological assessment of rat kidney tissue after treatment with vancomycin (VAN) alone, piperacillin/tazobactam (TZP) alone or TZP in combination with VAN (VAN+TZP). (a) Quantitative analysis of histopathology score in kidney tissues of rats. Values are expressed as mean ± SD; *P < 0.044 versus saline. Representative photomicrographs of haematoxylin and eosin-stained rat kidney sections. (b) Normal histology of kidney tissue in control rats administered normal saline, (c) tubular casts (arrow, ×100) in cortex of rats treated with TZP 1400 mg/kg IP once daily for 3 days, (d) tubular dilatation, tubular degeneration (arrows) and tubular basophilia (asterisk, ×100) in cortex of rats treated with VAN 150 mg/kg IV once daily for 3 days, and (e) tubular dilatation, tubular degeneration (arrows, ×100) in cortex of rats treated with VAN+TZP once daily for 3 days. This figure appears in colour in the online version of JAC and in black and white in the printed version of JAC.