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. 2021 Mar 20;144(8):2284–2290. doi: 10.1093/brain/awab120

Figure 3.

Figure 3

Comparison of carbazole (3H-PI2620, 3H-RO948) and isoquinolinamine (3H-MK6240, 3H-JNJ067) bearing tau tracers to basal ganglia sections from cases with Alzheimer’s disease. Representative images showing immunohistochemistry staining with (A) AT8, (B) total tracer binding, (C) self-block with the non-radiolabelled analogue of each tracer, and (D) MAOB inhibition with l-deprenyl. Scale bar = 10 mm. AD = Alzheimer’s disease; DEP = l-deprenyl block; NSB = non-specific binding after self-block; TB = total binding.