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. 2020 Jan 13;75(4):787–806. doi: 10.1093/jac/dkz544

Figure 14.

Figure 14.

Inhibition of 30S assembly in vitro by aminoglycosides. Sucrose gradient sedimentation profiles of subunits reconstituted with [3H]-uridine-labelled 16S rRNA. (a) Reconstitution of 30S subunits (filled circles) by incubation at 42°C and reconstitution of an RI particle (open squares) by incubation at 4°C. (b) Reconstitution in the presence of neomycin at 0.4 μg/mL. (c) Reconstitution in the presence of paromomycin at 0.4 μg/mL. Reproduced with permission from Springer Nature, reference 136.