Figure 4.

Perturbations of cell envelope biosynthesis in the polymyxin-resistant K. pneumoniae clinical isolates. Purple boxes show the metabolites that were approximately 2-fold less abundant in the polymyxin-resistant isolates than in their respective susceptible isolates; red boxes show the metabolites that were at least 2-fold more abundant in the polymyxin-resistant isolates than in their respective susceptible isolates. *FC ≥ 2, P < 0.05. Black boxes indicate the detected metabolites across three paired isolates but not different between polymyxin-resistant and -susceptible isolates. This figure appears in colour in the online version of JAC and in black and white in the print version of JAC.