Table 3.
Distribution of HPV Genotypes According to Different Periods in Women Under 30 with CIN3
| HPV Genotypes | 2007–2010 n (%) | 2011–2014 n (%) | 2015–2018 n (%) | P value |
|---|---|---|---|---|
| Sample Size (144) | Sample Size (180) | Sample Size (150) | ||
| HPV-16/18 | 112 (77.8) | 124 (68.9) | 99 (66.0) | 0.027 |
| HPV-31/33/35/52/58/67* | 17 (11.8) | 32 (17.8) | 28 (18.7) | 0.112 |
| HPV-39/45/59/68/70** | 7 (4.9) | 10 (5.6) | 4 (2.7) | 0.354 |
| HPV-31/33/45/52/58*** | 14 (9.7) | 28 (15.6) | 24 (16.0) | 0.122 |
| HPV-26/30/53/67/70/73/82/85**** | 7 (4.9) | 2 (1.1) | 2 (1.3) | 0.046 |
| HPV-6/11/40/42/43/44/54/55/61***** | 14 (9.7) | 28 (15.6) | 24 (16.0) | 0.122 |
Notes: *Genetically related to HPV16; **Genetically related to HPV18; ***High-risk-types included in the nonavalent vaccine; ****Possibly carcinogenic HPV; *****Low-risk HPV.
Abbreviations: HPV, Human Papillomavirus; CIN, cervical intraepithelial neoplasia.