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. 2021 Sep 16;14:3763–3771. doi: 10.2147/IDR.S326851

Table 4.

Age-Related Trend of HPVs According to Different Periods in Women Under 30 with CIN3

HPV Genotypes and Age-Groups 2007–2010 n (%) 2011–2014 n (%) 2015–2018 n (%) P value
Sample Size (144) Sample Size (180) Sample Size (150)
HPV-16/18 Age < 25 78 (77.2) 38 (71.7) 17 (68.0) 0.284
Age 25–29 34 (79.1) 86 (67.7) 82 (65.6) 0.145
HPV-31/33/35/52/58/67* Age < 25 12 (11.9) 10 (18.9) 5 (20.0) 0.197
Age 25–29 5 (11.6) 22 (17.3) 23 (18.4) 0.364
HPV-39/45/59/68/70** Age < 25 5 (5.0) 1 (1.9) 0 (0.0) 0.159
Age 25–29 2 (4.7) 9 (7.1) 4 (3.2) 0.412
HPV-31/33/45/52/58*** Age < 25 10 (9.9) 9 (17.0) 6 (24.0) 0.048
Age 25–29 4 (9.3) 19 (15.0) 18 (14.4) 0.532
HPV-26/30/53/67/70/73/82/85**** Age < 25 4 (4.0) 0 (0.0) 0 (0.0) 0.107
Age 25–29 3 (7.0) 2 (1.6) 2 (1.6) 0.108
HPV-6/11/40/42/43/44/54/55/61***** Age < 25 3 (3.0) 3 (5.7) 1 (4.0) 0.604
Age 25–29 0 (0.0) 6 (4.7) 1 (0.8) 0.606

Notes: *Genetically related to HPV16; **Genetically related to HPV18; ***High-risk- types included in the nonavalent vaccine; ****Possibly carcinogenic HPV; *****Low-risk HPV.

Abbreviations: HPV, Human Papillomavirus; CIN, cervical intraepithelial neoplasia.