TABLE 2.

Use of sulfonylurea and the risk for out‐of‐hospital cardiac arrest compared to use of metformin in monotherapy

	Cases	Controls	Crude OR	Adjusted OR
	(n = 219)	(n = 697)	(model 1)	(model 2)
Metformin alone	110 (50.2)	275 (39.5)	1.0 (reference)	1.0 (reference)
Sulfonylurea drugs	109 (49.8)	422 (60.5)	0.7 (0.5–0.9)	0.6 (0.5–0.9)
Sulfonylurea drugs alone	43 (19.6)	172 (24.7)	0.6 (0.4–0.9)	0.6 (0.4–0.9)
Sulfonylurea drugs + metformin	66 (30.1)	250 (35.9)	0.7 (0.5–1.0)	0.6 (0.4–0.9)

Use of metformin and/or sulfonylurea drugs was defined as use within 90 days before the index date.

Model 1: OR adjusted for age and sex.

Model 2: OR adjusted for age, sex, use of cardiovascular drug use, Vaughan‐Williams class 1 or 3 antiarrhythmic drugs and non‐cardiac QT‐prolonging drugs.