FIGURE 1.
Cytokine analysis in persistent vs early chronic GVHD and healthy volunteer. Graph comparing levels of 7 selected cGVHD biomarkers (in pg/ml) among individuals with no disease (ND), early cGVHD (<1 year) (E) and persistent cGVHD >7 years (L) using Wilcoxon rank sum test. A total of 52 early and 26 persistent cGVHD patients were tested with the ELISA panels. Each bar represents the SD for the measurement within each group and solid line within the bar stands for the median value. Vertical lines represent the range of measurements. BAFF and CXCL10 levels were significantly higher in the early cGVHD group compared to persistent cGVHD group. IL-6, CXCL9, BAFF, CXCL10, MCP-1 and ST2 were all significantly higher in the early cGVHD group than in healthy volunteers