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. Author manuscript; available in PMC: 2021 Sep 21.
Published in final edited form as: ACS Chem Biol. 2020 Apr 6;15(4):856–861. doi: 10.1021/acschembio.0c00044

Table 2.

Toxicity of Electrophilic Fumarate Analogues and S-succination Agonist in HEK-293T Cells at 48 h.

fumarate 72 ± 11
maleate 11 ± 0.91
2-bromosuccinate 1.2 ± 0.44
ethyl fumarate 0.95 ± 0.31
methyl fumarate 0.91 ± 0.48
dimethyl fumarate 0.059 ± 0.011