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. 2021 Sep 1;86(18):12745–12761. doi: 10.1021/acs.joc.1c01308

Scheme 1. Previous rResults and Scope of This Work.

Scheme 1

General strategies employed to access C- or N-alkyl trihydroxipiperidines from the “masked dialdehyde” 8 and nitrone 10a derived thereof. This work: “one-pot” synthesis of C-erythrosyl N-alkyl nitrones 10 and their application to the synthesis of C,N-dialkylated azasugars 14 and 15.