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. Author manuscript; available in PMC: 2021 Nov 1.
Published in final edited form as: Psychol Rev. 2020 Jun 11;127(6):972–1021. doi: 10.1037/rev0000199

Figure 8:

Figure 8:

Simulation 1c: Asymmetric dopamine signaling for late-versus-early reward. (a) Empirical results adapted from Hollerman and Schultz (1998), Figure 6b with permission from Springer Nature: Nature Neuroscience, copyright 1998, showing an asymmetric pattern of firing for late (thin arrow) versus early (thick arrow) reward delivery. (b,c) Simulation results for late-versus-early reward respectively, capturing the empirical results. (d) Focus on the USTime_In input layer, representing the OFC bridging between CS and US, with a temporally-evolving, US-specific pattern that drives the VS patch expectations of US timing. When the US arrives early, it resets this US timing representation, thereby preventing VS patch firing.