TABLE 1.
Chemokine expression in mouse and human culture adapted mesenchymal stromal cell (MSCs)
| Human MSC | Mouse MSC | ||||
|---|---|---|---|---|---|
| Namea | Other name(s)a | restingb | +hPBMCc | restingb | +mPBMCd |
| CC chemokines | |||||
| CCL1 | I‐309, TCA‐3 | + | |||
| CCL2 | MCP‐1 | ++ | ++ | +++ | ++++ |
| CCL3 | MIP‐1α | + | |||
| CCL4 | MIP‐1β | ++ | |||
| CCL5 | RANTES | + | ++ | + | ++++ |
| CCL6 | C10, MRP‐2 | ||||
| CCL7 | MARC, MCP‐3 | − | ++ | ++ | |
| CCL8 | MCP‐2 | − | ++ | ||
| CCL9/CCL10 | MIP‐1δ, CCF18 | + | + | ||
| CCL11 | Eotaxin | − | − | ||
| CCL12 | MCP‐5 | ++ | |||
| CCL13 | MCP‐4, NCC‐1 | − | |||
| CCL14 | HCC‐1, NCC‐2 | ||||
| CCL15 | MIP‐1δ, HCC‐2 | ||||
| CCL16 | NCC‐4 | ||||
| CCL17 | TARC, ABCD‐2 | − | + | ++ | |
| CCL18 | MIP‐4, PARC | + | |||
| CCL19 | MIP‐3β, Exodus‐3 | + | |||
| CCL20 | LARC, Exodus‐1 | ||||
| CCL21 | SLC, Exodus‐2 | − | |||
| CCL22 | MDC | + | |||
| CCL23 | MIP‐3 | − | |||
| CCL24 | Eotaxin‐2 | − | |||
| CCL25 | TECK | ||||
| CCL26 | Eotaxin‐3 | + | |||
| CCL27 | CTACK, Eskine | + | |||
| CCL28 | MEC | ||||
| CXC chemokines | |||||
| CXCL1 | GRO1 | − | +++ | +++++ | |
| CXCL2 | MIP‐2α/GRO2 | +++ | +++++ | ||
| CXCL3 | MIP‐2β/GRO3 | ||||
| CXCL4 | PF‐4 | ||||
| CXCL5 | ENA78 | ++++ | |||
| CXCL6 | GCP‐2 | ||||
| CXCL7 | NAP‐2 | ++ | |||
| CXCL8 | IL‐8/NAP‐1 | ++ | ++ | ||
| CXCL9 | MIG | − | ++ | +++++ | |
| CXCL10 | IP‐10 | + | ++ | +++++ | |
| CXCL11 | I‐TAC/IP‐9 | ++ | ++ | ||
| CXCL12 | SDF‐1 | + | + | + | |
| CXCL13 | BCA‐1 | − | ++ | ||
| CXCL14 | BRAK/bolekine | ||||
| CXCL15 | Lungkine, WECHE | ||||
| CXCL16 | SRPSOX | ||||
| CXCL17 | DMC, VCC‐1 | ||||
| C chemokines | |||||
| XCL1 | Lymphotactine α | ||||
| XCL2 | Lymphotactine β | ||||
| CX3C chemokines | |||||
| CX3CL1 | Fractalkine | ++ | ++++ | ||
Note: Qualitative units of expression: (−) absent, (+) to (++++), present with increasing levels. Boxes left blank were not evaluated.
a
Chemokine nomenclature informed by Laing and Secombes.75
b
Expression by MSCs in culture, informed by Chen et al.55
c
Expression human MSC co‐cultured with activated human PBMCs, informed by Chinnadurai et al.74
d
Expression mouse MSC co‐cultured with activated mouse PBMCs, informed by Ren et al.56