Table 1.
Characteristics of the HIV‐positive and HIV‐negative groups before and after propensity score matching analysis
| Variable | Before matching | P | After matching | P | ||
|---|---|---|---|---|---|---|
| HIV‐positive (n = 166) | HIV‐negative (n = 99) | HIV‐positive (n = 83) | HIV‐negative (n = 83) | |||
| Age (years) | 30 (25–36) | 29 (25–33.75) | 0.287 | 28 (25–33.75) | 29 (25–35.75) | 0.441 |
| Male gender | 156 (93.98) | 78 (78.79) | <0.001 | 76 (91.57) | 73 (87.95) | 0.442 |
| BMI (kg/m2) | 21.97 (20.28–24.61) | 21.97 (20.19–23.76) | 0.538 | 21.72 (19.88–24.03) | 21.93 (20.19–23.86) | 0.748 |
| SCr (μmol/L) | 71.69 (65.01–79.20) | 68.32 (58.31–75.93) | 0.001 | 70.10 (63.89–79.43) | 70.08 (62.21–76.69) | 0.424 |
| eGFR (mL/min/1.73 m2) | 116.57 (103.89–129.30) | 120.79 (114.43–137.37) | 0.005 | 122.11 (107.63–133.39) | 117.55 (109.55–133.14) | 0.988 |
| Serum albumin (g/L) | 46.50 (44.33–48.46) | 46.03 (44.56–48.01) | 0.480 | 46.61 (44.53–48.69) | 46.14 (44.61–48.22) | 0.537 |
| Uric acid (μmol/L) | 390.57 (337.24–449.72) | 343.01 (284.23–393.97) | <0.001 | 369.10 (304.51–417.43) | 354.38 (306.65–401.07) | 0.258 |
| TC (mmol/L) | 4.18 (3.67–4.61) | 4.12 (3.67–4.72) | 0.967 | 4.1900 (3.6150–4.6250) | 4.13 (3.65–4.72) | 0.954 |
| TG (mmol/L) | 1.31 (0.94–1.97) | 0.89 (0.67–1.13) | <0.001 | 1.29 (1.00 – 1.97) | 0.89 (0.69–1.17) | <0.001 |
| Current CD4 count (cells/μL) | 277 (180–393) | – | – | 292 (202.50–401.50) | – | – |
| HIV RNA (log10 copies/mL) | 4.38 (3.88–4.83) | – | – | 4.34 (3.73–4.77) | – | – |
| NAG:UCr (log10 U/g) | 1.45 (1.20–1.78) | 1.07 (0.80–1.29) | <0.001 | 1.39 (1.17–1.63) | 1.07 (0.80–1.29) | <0.001 |
| NGAL:UCr (log10 ng/g) | 3.93 (3.56–4.23) | 3.33 (2.90–3.75) | <0.001 | 3.92 (3.55–4.29) | 3.30 (2.90–3.80) | <0.001 |
| α1‐M:UCr (log10 ng/g) | 3.62 (3.41–3.83) | 3.17 (2.79–3.40) | <0.001 | 3.57 (3.36–3.79) | 3.19 (2.79–3.42) | <0.001 |
| KIM‐1:UCr (log10 ng/g) | 2.66 (2.40–2.87) | 2.45 (2.13–2.86) | 0.008 | 2.64 (2.44–2.92) | 2.42 (2.12–2.87) | 0.011 |
| EGF:UCr (log10 μg/g) | 3.89 (3.73–4.04) | 3.81 (3.60–3.97) | 0.005 | 3.94 (3.81–4.08) | 3.80 (3.59–3.98) | <0.001 |
| THP:UCr (log10 μg/g) | 3.05 (2.82–3.26) | 3.07 (2.73–3.24) | 0.542 | 3.05 (2.79–3.27) | 3.07 (2.70–3.25) | 0.721 |
| Abnormal ACR | 8 (4.82) | 0 (0) | 0.027 | 4 (4.82) | 0 (0) | 0.120 |
Continuous data are presented as median (interquartile range), and categorical variables are presented as n (%). P‐values are from χ2 tests for categorical variables and Mann–Whitney U tests for continuous variables.
ACR, albumin‐to‐creatinine ratio; BMI, body mass index; UCr, Urine creatinine; eGFR, estimate glomerular filtration rate; SCr, serum creatinine; TC, total cholesterol; TG, triglycerides; UA, uric acid; NAG, N‐acetyl‐β‐D‐glucosaminidase; NGAL, neutrophil gelatinase‐associated lipocalin; α1‐M, alpha 1‐microglobulin; KIM‐1, kidney injury molecule‐1; THP, Tamm–Horsfall protein; EGF, epidermal growth factor.