TABLE 1.
Demographics and disease characteristics of patients with HNSCC from Milan, Italy
| Number of patients, n = 259 (%) | |
|---|---|
| Sex | |
| Male | 198 (76) |
| Female | 61 (24) |
| Age, years – median (range) | 62 (24–93) |
| ECOG performance status | |
| 0 | 51 (20) |
| 1 | 195 (75) |
| 2 | 12 (4) |
| 3 | 1 (1) |
| Primary tumor location | |
| Oral cavity | 97 (37) |
| Oropharynx | 85 (33) |
| HPV‐positive | 28 (11) |
| Hypopharynx | 22 (8) |
| Larynx | 50 (20) |
| Carcinoma of unknown primary | 5 (2) |
| AJCC clinical stage | |
| I | 20 (8) |
| II | 23 (9) |
| III | 17 (6) |
| IV | 198 (76) |
| Unknown | 1 (1) |
| Intent to treatment | |
| Radical | 222 (86) |
| Palliative | 37 (14) |
| Surgery | 129 (50) |
| Radiotherapy | 173 (67) |
| Dose (Gy) – median (range) | 62.1 (0–135) |
| Type of recurrence | |
| Local/nodal/soft tissue/tracheal | 188 (72) |
| Lung | 60 (23) |
| Bones | 15 (6) |
| Hepatic | 7 (3) |
| Intracranial | 4 (1) |
| Other | 9 (3) |
| Size of local recurrence | |
| <2 cm | 5 (2) |
| 2–2.9 cm | 24 (9) |
| 3–5 cm | 74 (28) |
| >5 cm | 140 (54) |
| Recurrence in field | 143 (55) |
Abbreviations: AJCC, American Joint Committee on Cancer; ECOG, Eastern Cooperative Oncology Group; HNSCC, head and neck squamous cell carcinoma; HPV, human papillomavirus.
Source: “Bleeding in recurrent and/or metastatic patients with head and neck squamous cell carcinoma: the experience at the Istituto Nazionale Tumori of Milan.”