FIGURE 7.

Infiltrating monocytes and resident microglia exhibits TLR4 receptors in injured cortex. (a) Schematic of the experimental protocol. (b) Flow cytometry analysis of immune cells gated on CD45⁺ from a representative TBI ipsilateral cortex. (c) Quantification of the percentage of cell types expressing TLR4 receptors of each cell population among CD45⁺ cells (microglia: CD11b^intCD45^int; lymphocytes: CD11b^negCD45^hi; neutrophils: CD11b^hiCD45^hiLy‐6G^hi; and infiltrating monocytes: CD11b^hiCD45^hiLy‐6G‐F4/80 + Ly‐6C^hi). Open dots on scatterplots are representative of each ipsilateral brain of n = 5 mice and depict the % of TLR4⁺ cells exhibiting extracellular receptor expression within each population