Table 2.
GO: Biological Process | Enriched in ICM | Compared with DCM | Only Significant in ICM | ||||
---|---|---|---|---|---|---|---|
GS | NES | p | GS | NES | p | ||
Cell proliferation and differentiation | |||||||
Positive regulation of cell population proliferation | 27 | 1.753 | 0.000 | 29 | 1.338 | 0.087 | Yes |
Regulation of cell population proliferation | 46 | 1.565 | 0.013 | 51 | 0.998 | 0.487 | Yes |
Negative regulation of cell population proliferation | 21 | 1.548 | 0.046 | 25 | 0.664 | 0.904 | Yes |
Regulation of MAPK cascade | 29 | 1.712 | 0.005 | 30 | 0.803 | 0.756 | Yes |
Positive regulation of MAPK cascade | 25 | 1.624 | 0.011 | 26 | 0.744 | 0.816 | Yes |
Epithelial cell differentiation | 26 | 1.523 | 0.032 | 29 | 0.959 | 0.548 | Yes |
Structure organization | |||||||
Extracellular structure organization | 37 | 1.796 | 0.003 | 44 | 1.281 | 0.113 | Yes |
Anatomical structure formation involved in morphogenesis | 41 | 1.479 | 0.036 | 47 | 0.832 | 0.755 | Yes |
Tube development | 44 | 1.437 | 0.042 | 49 | 0.958 | 0.572 | Yes |
Others | |||||||
Signal transduction by protein phosphorylation | 34 | 1.473 | 0.037 | 37 | 1.364 | 0.084 | Yes |
Biological adhesion | 82 | 1.459 | 0.018 | 89 | 1.147 | 0.231 | Yes |
Abbreviations: ICM, ischemic cardiomyopathy; DCM, dilated cardiomyopathy; GO, gene ontology; GS, gene size; NES, normalized enrichment score.