FIGURE 2.

l‐cysteine and NaHS cause a further increase in tension of phenylephrine (PE)‐contracted mouse carotid artery rings. Concentration–response curve of (a) l‐cysteine (10 nM to 300 μM) and (b) NaHS (10 nM to 300 μM) on a stable tone of PE (1 μM). The increase in contraction was blunted by the mechanical endothelium removal for both l‐cysteine (n = 6 mice) and NaHS (n = 6 mice). Values shown are means ± SEM and expressed as δ increase in tension over PE contraction (dyne/mg tissue). *P < 0.05 significantly different as indicated; two‐way ANOVA with Bonferroni's post hoc test