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. 2013 Dec 28;2013(12):CD006577. doi: 10.1002/14651858.CD006577.pub3

Summary of findings 1. Music versus standard care for coronary heart disease.

Music versus standard care for coronary heart disease
Patient or population: people with coronary heart disease
Settings:Intervention: music versus standard care
Outcomes Illustrative comparative risks* (95% CI) Relative effect
(95% CI) No of Participants
(studies) Quality of the evidence
(GRADE) Comments
Assumed risk Corresponding risk
Control Music versus standard care
Psychological Distress
POMS   The mean psychological distress in the intervention groups was
1.26 lower
(2.30 to 0.22 lower)   228
(5 studies) ⊕⊕⊝⊝
low1  
Anxiety (all measures)
NRS, VAS, HADS, STAI   The mean anxiety (all measures) in the intervention groups was
0.70 standard deviations lower
(1.17 to 0.22 lower)   353
(10 studies) ⊕⊝⊝⊝
very low1,2,3  
State anxiety (MI patients)
STAI   The mean state anxiety (MI patients) in the intervention groups was
5.87 lower
(7.99 to 3.75 lower)   243
(6 studies) ⊕⊕⊝⊝
low1  
Heart rate
bpm   The mean heart rate in the intervention groups was
3.62 lower
(6.28 to 0.95 lower)   828
(13 studies) ⊕⊝⊝⊝
very low1,2,3  
Respiratory rate
breaths per minute   The mean respiratory rate in the intervention groups was
2.50 lower
(3.61 to 1.39 lower)   442
(7 studies) ⊕⊝⊝⊝
very low1,4  
Systolic blood pressure   The mean systolic blood pressure in the intervention groups was
5.52 lower
(7.43 to 3.60 lower)   775
(11 studies) ⊕⊕⊝⊝
low1  
Pain
VAS, NRS   The mean pain in the intervention groups was
0.43 standard deviations lower
(0.80 to 0.05 lower)   562
(8 studies) ⊕⊝⊝⊝
very low1,3,5  
*The basis for the assumed risk (e.g. the median control group risk across studies) is provided in footnotes. The corresponding risk (and its 95% confidence interval) is based on the assumed risk in the comparison group and the relative effect of the intervention (and its 95% CI).
CI: Confidence interval;
GRADE Working Group grades of evidence
High quality: Further research is very unlikely to change our confidence in the estimate of effect.
Moderate quality: Further research is likely to have an important impact on our confidence in the estimate of effect and may change the estimate.
Low quality: Further research is very likely to have an important impact on our confidence in the estimate of effect and is likely to change the estimate.
Very low quality: We are very uncertain about the estimate.

1The majority of the trials were assessed as being at high risk of bias
2Results were inconsistent across studies as evidenced by I² = 77%.
3Wide confidence interval
4Results were inconsistent across studies as evidenced by I² = 79%.
5Results were inconsistent across studies as evidenced by I² = 81%.