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. 2021 Sep 20;19:281. doi: 10.1186/s12951-021-01035-8

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© The Author(s) 2021

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 5 — Morphological evaluation of the injured spinal cord and locomotor functional assessment. The experimental model for rats (a). Representative BBB scores of rats from R-DHLA-AuNCs-Zn group at different time points (b) (n = 10, *p < 0.05, **p < 0.01 compared to SCI group). Representative bladder assays (c) of rats from R-DHLA-AuNCs-Zn group at different time points (n = 10, *p < 0.05, **p < 0.01 compared to SCI group). Images of the spinal cord of SCI rat model and R-DHLA-AuNCs-Zn adminstration groups (d). Quantification of the lesion area percentage (e) in two groups (n = 6,**p < 0.01 compared to SCI group). Quantification of the water content (f) in two groups (n = 6,**p < 0.01 compared to SCI group). **P < 0.01;***P < 0.001. Data presented as mean ± SD. (n = 6 /group)