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. Author manuscript; available in PMC: 2021 Sep 21.
Published in final edited form as: Dev Neurosci. 2020 Mar 11;41(5-6):263–273. doi: 10.1159/000506227

Figure 2.

Figure 2.

Experimental Design. In Experiment 1, NVHL and SHAM rats were randomized to ENR vs. IMP conditions. 1A rats (PD28-SAL) were tested in the novel arena before and after saline (SAL) injections at Postnatal Day 28 (PD28); 1B (PD42-SAL) were tested at PD42; and 1C (PD56-SAL) were tested at PD56. 2A (PD56-COC) and 2B (PD84-SENS) rats were all tested in the novel arena before and after cocaine (COC) injections, but with 2A rats tested at PD 56 with no prior cocaine history, and 2B rats tested at PD84 after having experienced as sensitizing series of 10 cocaine injections (PD56-PD68).