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. 2021 Mar 9;151(5):1277–1285. doi: 10.1093/jn/nxaa444

TABLE 1.

Associations between zinc and Hb concentrations in PSC and nonpregnant WRA, BRINDA project1

PSC WRA
Country n   β  zinc (95% CI) P value n   β  zinc (95% CI) P value
Afghanistan 600 −0.03 (−0.26, 0.20) 0.79 953 0.02 (−0.09, 0.13) 0.66
Azerbaijan 1015 0.03 (−0.05, 0.11) 0.41
Bangladesh 298 0.23 (−0.01, 0.47) 0.06 719 0.14 (0.06, 0.23) <0.001
Burkina Faso 118 0.23 (0.04, 0.43) 0.02 125 0.20 (−0.05, 0.45) 0.12
Cambodia 327 0.09 (−0.05, 0.23) 0.22 427 −0.02 (−0.14, 0.10) 0.75
Cameroon 729 0.25 (0.09, 0.42 0.003 736 0.14 (−0.01, 0.28) 0.06
Colombia 3569 0.02 (−0.01, 0.05) 0.18
Ecuador 2017 0.14 (0.08, 0.20) <0.001 7267 0.24 (0.19, 0.30) <0.001
India 323 0.06 (−0.07, 0.18) 0.37
Malawi 1063 0.11 (0.04, 0.18) 0.001 751 0.21 (0.12, 0.31) <0.001
Mexico 1163 0.04 (0.00, 0.09) 0.035 1679 −0.05 (−0.13, 0.03) 0.26
Mongolia 227 0.47 (0.47, 0.47) <0.001
Pakistan 7158 −0.01 (−0.04, 0.02) 0.56 7129 0.01 (−0.02, 0.04) 0.44
United Kingdom 838 0.10 (0.03, 0.16) 0.003
Vietnam 374 0.14 (0.04, 0.24) 0.01 1478 0.10 (0.05, 0.16) <0.001
1

Zinc concentrations in preschool children were adjusted for inflammation in the following countries: Afghanistan, Azerbaijan, Burkina Faso, Cambodia, Cameroon, Ecuador, India, Malawi, and Vietnam. Zinc concentrations were not adjusted for inflammation in WRA. Hb concentrations were adjusted for altitude and smoking, where those data were available (altitude data were available in Afghanistan, Azerbaijan, Colombia, Ecuador, United Kingdom, Malawi, and Mexico; smoking data were available in Colombia, Ecuador, and Mexico). Zinc and Hb concentrations and age were centered around zero and reduced to an SD = 1 for each country separately. BRINDA, Biomarkers Reflecting Inflammation and Nutritional Determinants of Anemia; Hb, hemoglobin; PSC, preschool children; WRA, women of reproductive age.