Table 3. The association between MBL2 codon 54 rs1800450 and promoter -221 rs7096206 genotypes and the clinical and biochemical features of filarial chyluria patients .
Variables | Wild (AA) (n=64) (%) | Hetero (AB) (n=31) (%) | Mutant (BB) (n=6) (%) | p-value | Wild (YY) (n=51) (%) | Hetero (YX) (n=44) (%) | Mutant (XX) (n=6) (%) | p-value |
Type of presentation: primary recurrent | 39 (60.9) 25 (39.1) | 11 (35.5) 20 (64.5) | 2 (33.3) 4 (66.7) | 0.044 | 30 (58.8) 21 (41.2) | 18 (40.9) 26 (59.1) | 4 (66.7) 2 (33.3) | 0.163 |
Grade of chyluria: I II III | 29 (45.3) 33 (51.6) 2 (3.1) | 9 (29.0) 15 (48.4) 7 (22.6) | 1 (16.7) 4 (66.7) 1 (16.7)` | 0.028 | 21 (41.2) 27 (52.9) 03 (5.9) | 16 (36.4) 21 (47.7) 7 (15.9) | 2 (33.3) 4 (66.7) 0 (0.0)` | 0.459 |
Duration of chyluria (months): mean± SD | 31.6±65.94 | 32.61±14.0 | 23.50±18.50 | 0.17 | 32.40±63.86 | 32.16±61.90 | 18.30±26.72 | 0.38 |
Number of previous episodes: mean± SD | 1.42±1.27 | 2.0 ± 2.0 | 1.83±2.50 | 0.17 | 1.43±1.25 | 1.82±1.40 | 1.80±1.47 | 0.39 |
Urine triglycerides (g/dl): mean± SD | 196.4±4 | 279.60±218.0 | 319.70±279.8 | 0.001 | 206.0±181.30 | 250.49±170.60 | 271.20±265.70 | 0.23 |
Urine cholesterol (g/dl): mean± SD | 18.2±16.86 | 21.29±19.1 | 20.41±22.0 | 0.28 | 21.80±23.0 | 16.48±8.20 | 18.26±8.94 | 0.85 |