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. 2021 Aug 18;13(8):e17292. doi: 10.7759/cureus.17292

Table 3. The association between MBL2 codon 54 rs1800450 and promoter -221 rs7096206 genotypes and the clinical and biochemical features of filarial chyluria patients .

MBL2: Mannose binding lectin 2

Variables Wild (AA) (n=64) (%) Hetero (AB) (n=31) (%) Mutant (BB) (n=6) (%) p-value Wild (YY) (n=51) (%) Hetero (YX) (n=44) (%) Mutant (XX) (n=6) (%) p-value
Type of presentation: primary recurrent 39 (60.9) 25 (39.1) 11 (35.5) 20 (64.5) 2 (33.3) 4 (66.7) 0.044 30 (58.8) 21 (41.2) 18 (40.9) 26 (59.1) 4 (66.7) 2 (33.3) 0.163
Grade of chyluria: I II III 29 (45.3) 33 (51.6) 2 (3.1) 9 (29.0) 15 (48.4) 7 (22.6) 1 (16.7) 4 (66.7) 1 (16.7)` 0.028 21 (41.2) 27 (52.9) 03 (5.9) 16 (36.4) 21 (47.7) 7 (15.9) 2 (33.3) 4 (66.7) 0 (0.0)` 0.459
Duration of chyluria (months): mean± SD 31.6±65.94 32.61±14.0 23.50±18.50 0.17 32.40±63.86 32.16±61.90 18.30±26.72 0.38
Number of previous episodes: mean± SD 1.42±1.27 2.0 ± 2.0 1.83±2.50 0.17 1.43±1.25 1.82±1.40 1.80±1.47 0.39
Urine triglycerides (g/dl): mean± SD 196.4±4 279.60±218.0 319.70±279.8 0.001 206.0±181.30 250.49±170.60 271.20±265.70 0.23
Urine cholesterol (g/dl): mean± SD 18.2±16.86 21.29±19.1 20.41±22.0 0.28 21.80±23.0 16.48±8.20 18.26±8.94 0.85