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. 2021 Aug 18;13(8):e17292. doi: 10.7759/cureus.17292

Table 4. Association between MBL2 codon 54 rs1800450 and promoter -221 rs7096206 genotypes and outcome of medical therapy.

MBL2: Mannose binding lectin 2

MBL2 gene Medical therapy (n=101)
n =101 (%) Remission (Group A) (n=66) Recurrence/failure (Group B) (n=35) OR (95% CI) p-value
Codon 54 (rs1800450) Wild (AA) Hetero (AB) Mutant (BB) AB+BB 64 31 6  37 48 (75) 16 (51.6) 2 (33.3) 18 16 (25) 15 (48.4) 4 (66.7) 19 Ref. 2.81 (1.14-6.94) 6.00 (1.00-35.91) 3.17 (1.34-7.47) 0.034 0.050 0.009
-221 (rs7096206 ) Wild (YY) Hetero (YX) Mutant (XX) YX+XX 51 44 6 50 39 (76.5) 23 (52.3) 4 (66.7) 27 12 (23.5) 21 (47.7) 2 (33.3) 23 Ref. 2.97 (1.23-7.13) 1.63 (0.26-9.99) 2.76 (1.80-6.50) 0.018 0.630 0.020