Table 4. Association between MBL2 codon 54 rs1800450 and promoter -221 rs7096206 genotypes and outcome of medical therapy.
MBL2 gene | Medical therapy (n=101) | ||||
n =101 (%) | Remission (Group A) (n=66) | Recurrence/failure (Group B) (n=35) | OR (95% CI) | p-value | |
Codon 54 (rs1800450) Wild (AA) Hetero (AB) Mutant (BB) AB+BB | 64 31 6 37 | 48 (75) 16 (51.6) 2 (33.3) 18 | 16 (25) 15 (48.4) 4 (66.7) 19 | Ref. 2.81 (1.14-6.94) 6.00 (1.00-35.91) 3.17 (1.34-7.47) | 0.034 0.050 0.009 |
-221 (rs7096206 ) Wild (YY) Hetero (YX) Mutant (XX) YX+XX | 51 44 6 50 | 39 (76.5) 23 (52.3) 4 (66.7) 27 | 12 (23.5) 21 (47.7) 2 (33.3) 23 | Ref. 2.97 (1.23-7.13) 1.63 (0.26-9.99) 2.76 (1.80-6.50) | 0.018 0.630 0.020 |