Solimene 1983.

Study characteristics
Methods	Parallel design (2 arms) Country: Brazil Follow‐up period: 12 hours
Participants	Randomly assigned: N = 43 Lidocaine group: 48.82% (21/43) No lidocaine group: 51.1% (22/43) Age, years, mean (standard error or standard deviation: not stated) Lidocaine group: 57 (10) No lidocaine group: 55 (11) Gender, male, % (n/N) Total group: 86.04 (37/43) Lidocaine group: 85.7 (18/21) No lidocaine group: 86.36 (19/22) Inclusion criteria: based on clinic criteria and electrocardiogram (no additional details) Exclusion criteria: not stated
Interventions	Lidocaine 2 doses of 100 mg intravenous bolus,15 minutes apart Continuous infusion 2 to 4 mg/min, in 5% glucose and water for 24 hours, initiated at the time of the first 100 mg Control group: no lidocaine Co‐intervention: cardioversion
Outcomes	Ventricular extrasystoles Ventricular tachycardia Ventricular fibrillation
Notes	Sample size calculation a priori: not reported Sponsor: not reported Trial conduction dates: not stated E‐mail was sent to the main trial author
Risk of bias
Bias	Authors' judgement	Support for judgement
Random sequence generation (selection bias)	Unclear risk	"... os pacientes foram seleccionados, ao acaso,..." (page 377) Insufficient information about the sequence generation process to permit judgement of ‘low risk’ or ‘high risk’
Allocation concealment (selection bias)	Unclear risk	Insufficient information to permit judgement of ‘low risk’ or ‘high risk’
Blinding of participants and personnel (performance bias) All outcomes	Unclear risk	Insufficient information to permit judgement of ‘low risk’ or ‘high risk’
Blinding of outcome assessment (detection bias) All outcomes	Unclear risk	Insufficient information to permit judgement of ‘low risk’ or ‘high risk’
Incomplete outcome data (attrition bias) All outcomes	Unclear risk	The report gave the impression that no dropouts or withdrawals had occurred, but this was not specifically stated
Selective reporting (reporting bias)	High risk	The study report fails to include results for a key outcome that would be expected to have been reported for such a study This study did not report mortality data
Other bias	High risk	Design bias and bias in data presentation (Porta 2008).