Table 2.
Top 15 features for HPV status prediction and notation of involvement in HPV status-specific prognostic prediction in experiment 2.
| Feature names (parameters) | ROI | Rank sum p-value (unadjusted) | Contribute to DFS prediction for HPV+? | Contribute to DFS prediction for HPV−? |
|---|---|---|---|---|
| CoLlAGe (Std of sum-variance) | Peritumoral 0–5 mm | 3.0 × 10−7 | ✘ | ✘ |
| Haralick (mean of Info1) | Peritumoral 0–5 mm | 1.3 × 10−8 | ✘ | ✘ |
| Gabor (median, λ = 3, θ = 0.1 rad) | Peritumoral 5–10 mm | 8.5 × 10−6 | ✓ | ✓ |
| CoLlAGe (skewness of sum-average) | Peritumoral 5–10 mm | 0.0046 | ✘ | ✓ |
| CoLlAGe (kurtosis of diff-average) | Peritumoral 0–5 mm | 1.78 × 10−4 | ✘ | ✘ |
| Haralick (Std of Info1) | Peritumoral 5–10 mm | 4.7 × 10−4 | ✘ | ✘ |
| Gabor (skewness, λ = 5, θ = 0.0 rad) | Peritumoral 10–15 mm | 0.001 | ✘ | ✘ |
| Laws (median of E5L5) | Peritumoral 10–15 mm | 0.0335 | ✘ | ✘ |
| Laws (skewness L5R5) | Peritumoral 0–5 mm | 6.5 × 10−4 | ✘ | ✘ |
| Gabor (kurtosis, λ = 3, θ = 0.6 rad) | Peritumoral 0–5 mm | 4.8 × 10−6 | ✘ | ✓ |
| CoLlAGe (Std of sum-average) | Peritumoral 0–5 mm | 5.3 × 10−5 | ✓ | ✘ |
| Haralick (median of info1) | Intratumoral | 1.8 × 10−5 | ✘ | ✘ |
| CoLlAGe (skewness of diff-variance) | Intratumoral | 4.4 × 10−4 | ✘ | ✘ |
| Gray (median of mean intensity) | Intratumoral | 0.001 | ✓ | ✘ |
| Haralick (skewness of diff-variance) | Intratumoral | 0.005 | ✘ | ✘ |