Table 1:
| SUBSTUDY | Sample Size (N) (SCZ/Control) | AgeSCZ | Agecontrol | SexSCZ (N) | Sexcontrol (N) |
|---|---|---|---|---|---|
|
| |||||
| Neanderthal DNA & Schizophrenia Diagnosis | |||||
| NIMH | 1367 (537/830) | 34.1±10.1 yrs | 31.1±9.7 yrs | 397 M, 140 F | 381 M, 449 F |
| Ashkenazi Jewish | 3052 (1027/2025) | 45.3±13.9 yrs | 42.4±16.7 yrs | 649 M, 378 F | 1482 M, 543 F |
| GAIN Schizophrenia | 2550 (1173/1377) | 43.8±11.3 yrs | 51.1±17.0 yrs | 820 M, 353 F | 633 M, 744 F |
| Non-GAIN Schizophrenia* | 2393 (1100/1293) | 43.0±12.0 yrs | 49.9±15.8 yrs | 766 M, 334 F | 644 M, 649 F |
| Total | 9362 (3837/5525) | 42.6±12.6 yrs | 44.6±17.1 yrs | 2632 M/1205 F | 3140 M, 2385 F |
|
| |||||
| Neanderthal DNA & Schizophrenia symptoms (NIMH subsample) | 49 (49/0) | 29.9±9.0 yrs | N/A | 37 M, 12 F | N/A |
|
| |||||
| Neanderthal DNA & FDOPA PET (NIMH subsample) | 173 (0/173) | N/A | 36.5±12.4 yrs | N/A | 86 M, 87 F |
*
Age was not provided for 1.2% of the samples from the non-GAIN Schizophrenia dataset.
Abbreviations:
SCZ = Schizophrenia
FDOPA = 18F-fluorodopa
PET = positron emission tomography
Yrs = years
M = Male F = Female