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. 2021 Aug 22;8(9):ofab438. doi: 10.1093/ofid/ofab438

Table 3.

Ad Hoc Analysis of the Presence and Concentration of Vaginal Lactobacilli, Other Cervicovaginal Microbiota, and Sexually Transmitted Infection in Participants With a Moderate to High Concentration of Schistosoma DNA (Ct < 35) Compared With FGS-Negative Participants

Organism No. (%) and Concentrationa FGS Negative (n = 158) FGS With Ct < 35 (n = 16) P Valueb
L. crispatus Presence 49 (31.0) 6 (37.5) .60
Median (IQR) 1.1×107 (2.6×105–7.0×108) 1.2×106 (3.0×105–2.0×107) .28
Log-concentration mean 16.38 14.27 .19
L. iners Presence 113 (71.5) 11 (68.75) .82
Median (IQR) 2.8×108 (3.9×107–1.6×109) 7.5×107 (3.6×106–7.5×108) .30
Log-concentration mean 18.98 17.86 .21
G. vaginalis Presence 115 (72.8) 13 (81.3) .46
Median (IQR) 8.1×106 (7.7×105–4.8×107) 1.5×107 (3.8×106–3.1×108) .11
Log-concentration mean 15.74 17.45 .03
A. vaginae Presence 112 (70.9) 13 (81.3) .38
Median (IQR) 5.8×107 (8.7×106–2.0×108) 1.6×108 (1.6×107–2.8×108) .70
Log-concentration mean 17.33 17.38 .95
T. vaginalis Presence 34 (21.5) 8 (50.0) .01
Median (IQR) 1.7×105 (56.9–6.3×106) 8085.0 (5210.0–1.0×106) .56
Log-concentration mean 10.88 10.09 .70
Vaginal microbiota with prevalence <20%
N. gonorrheae Presence 12 (7.6) 0 (0.0) .61
C. trachomatis Presence 13 (8.2) 2 (12.5) .63
M. genitalium Presence 7 (4.4) 0 (0.0) 1.0
C. albicans Presence 8 (5.1) 2 (12.5) .23

Abbreviations: Ct, cycle threshold; FGS, female genital schistosomiasis; IQR, interquartile range.

aConcentrations are expressed in genome equivalents/mL.

bFor species with >20% prevalence, P values for presence, median (IQR), and log-concentration mean are from the chi-square test, rank-sum test, and t test, respectively. For species with <20% prevalence, P values for presence are from the Fisher exact test.