Table 4.

Ad Hoc Analysis of the Presence and Concentration of Vaginal Lactobacilli, Cervicovaginal Microbiota, and Sexually Transmitted Infection in Participants With Schistosoma DNA Detected in ≥2 Genital Specimens Compared With FGS-Negative Participants

Organism	No. (%) and Concentrationa	FGS Negative (n = 158)	≥2 PCR FGS (n = 16)	P Valueb
L. crispatus	Presence	49 (31.0)	7 (43.8)	.30
	Median (IQR)	1.1×107 (2.6×105–7.0×108)	1.9×106 (7.7×104–2.7×107)	.32
	Log-concentration mean	16.38	14.90	.34
L. iners	Presence	113 (71.5)	10 (62.5)	.45
	Median (IQR)	2.8×108 (3.9×107–1.6×109)	5.1×107 (9.0×105–1.1×108)	.03
	Log-concentration mean	18.98	17.00	.03
G. vaginalis	Presence	115 (72.8)	14 (87.5)	.20
	Median (IQR)	8.1×106 (7.7×105–4.8×107)	1.6×107 (1.1×106–3.6×108)	.29
	Log-concentration mean	15.74	16.85	.16
A. vaginae	Presence	112 (70.9)	11 (68.8)	.86
	Median (IQR)	5.8×107 (8.7×106–2.0×108)	1.6×108 (2.7×107–3.2×108)	.33
	Log-concentration mean	17.33	18.04	.36
T. vaginalis	Presence	34 (21.5)	8 (50.0)	.01
	Median (IQR)	1.7×105 (56.9–6.3×106)	5680.0 (2967.5–1.0×106)	.50
	Log-concentration mean	10.88	9.71	.56
Vaginal microbiota with prevalence <20%
N. gonorrheae	Presence	12 (7.6)	0 (0.0)	.61
C. trachomatis	Presence	13 (8.2)	2 (12.5)	.63
M. genitalium	Presence	7 (4.4)	0 (0.0)	1.0
C. albicans	Presence	8 (5.1)	1 (6.3)	.59

Abbreviations: FGS, female genital schistosomiasis; IQR, interquartile range; PCR, polymerase chain reaction.

^aConcentrations are expressed in genome equivalents/mL.

^bFor species with >20% prevalence, P values for presence, median (IQR), and log-concentration mean are from the chi-square test, rank-sum test and t test, respectively. For species with <20% prevalence, P values for presence are from the Fisher exact test.