Figure 2.
Construction and Biological Applications of Fluorophore-Protein Complexes
(A) Synthesis of CH-4T.
(B) NIR-II fluorescence images of CH-PEG and CH-4T in deioni1zed water, FBS, and PBS.
(C) Photographs and corresponding NIR-II fluorescence images of CH-4T in FBS and heated FBS. Reproduced with permission from Antaris et al.92 Copyright 2017 Springer Nature.
(D) Schematic of H2a-4T@Cetuximab complex used in NIR-II fluorescence imaging and PTT. Reproduced with permission from Zeng et al.93 Copyright 2018 Wiley-VCH.
(E) The schematic explanation for fluorescence enhancement by introducing quaternary ammonium salts. Reproduced with permission from Qu et al.94 Copyright 2019 Wiley-VCH.
(F) Schematic of CQ-4T/HSA complex for multifunctional biomedical imaging and surgical navigation in the NIR-II area. Reproduced with permission from Li et al.95 Copyright 2019 Wiley-VCH.