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. 2020 Apr 22;1(1):100009. doi: 10.1016/j.xinn.2020.04.009

Table 1.

The Size and Surface Groups of CDs Present in Food Items

Food Description Size (nm) Surface Groups Quantum Yield (%) Toxicity Reference
Chicken Heating at 200°C, 250°C, and 300°C in an oven 2.1–17.1 C=C; CO–NH 6.71–17.46 Cell viability decreased to 15%–33% after treatment with 4 mg mL−1 CDs Song et al.40
Beer Isolated from Snow, Harbin, Wernesgruner Dark, FAXE, and Yanjin 0.94–4.13 C=C; COOH;–OH;–NH2 1.42–3.92 No acute toxicity was observed in BALB/c mice after administration of a single dose of 2 g kg−1 body weight Wang et al.41
Beer Isolated from Tsingtao beer 1–5 –OH; –COOH; C–N–C; N–H 7.39 No obvious cytotoxicity was observed after treatment with 12.5 mg mL−1 CDs Wang et al.35
Coffee Isolated from Nescafe Original instant coffee ~4.4 C=C;C-O–C; COOH;–OH 5.5 No obvious cytotoxicity was observed after treatment with 20 mg mL−1 CDs Jiang et al.21
Beverages Isolated from Coca-Cola and Pepsi-Cola 4.7–5.0 C–O–C; C-O; C=C; –OH 3.3 and 4.3 No acute toxicity was observed in BALB/c mice after administration of a single dose of 2 g kg−1 body weight Li et al.36
Croaker Isolated from canned yellow croaker 1.8–5.8 C–O–C; C=O; –OH;CO–NH 9.7 Cell viability decreased to 80% after treatment with 0.125 mg mL−1 CDs Li et al.26
Duck Roasted at 170°C for 60 min ~1.3 C=O; C=C; CO–NH 4.4 Cong et al.29
Mature vinegar Isolated from Chinese mature vinegar 0.5–2.5 -OH;C=O; –COOH 5.71 Cao et al.30
Glucose and lysine Products of the Maillard reaction 2.3–6.8 O-H; O=C–O; C–O; O=C–O 16.30 Cell viability decreased to 80% after treatment with 10 mg mL−1 CDs Li et al.27
Lamb Heating at 200°C, 300°C, and 350°C in an oven 1.6–2.8 C=O; –NH; –OH 6–45 No obvious cytotoxicity was observed after treatment with 2 mg mL−1 CDs Wang et al.31
Pike Eel Heating at 160°C, 200°C, 230°C, 260°C, 300°C in an oven 1.75–4.2 C=O; C=C; C-O; –OH 12.86–80.16 No obvious cytotoxicity was observed after treatment with 20 mg mL−1 CDs Bi et al.33
Pizza Isolated from pizza ~3.33 C=O; –OH; –NH2; COOH 2.14 Cell viability decreased to 80.37% after treatment with 5 mg mL−1 CDs Cong et al.38
Hamburger Heating at 220°C, 260°C, 300°C in an oven 2.5–33.6 -OH; CO–NH;–NH 23.25–15.03 Cell viability decreased to 80% after treatment with 3.2 mg mL−1 CDs Li et al.37
Beverages Isolated from kvass, Pony Malta, Profit, etc. 5–39 -OH; C=O; C=C; C–O–C 1.48–11.9 No obvious cytotoxicity was observed after treatment with 20 mg mL−1 CDs Liao et al.22
Atlantic salmon Heating at 200°C in an oven 2.4–3.7 C=O; C=C; C–N 2.21–12.09 Cell viability decreased to 34% after treatment with 6 mg mL−1 CDs Song et al.25
Honey Isolated from honey ~3.2 C=C; –OH; –COOH 1.6 Mandani et al.32
Bakery Isolated from bakery products 5–20 Cell viability decreased to 80% after treatment with 0.4 mg mL−1 CDs Al-Hadi et al.23
Caramels Isolated from caramels 4.3–27.5 0.63–1.2 Sk et al.20
Beef Broth Isolated from beef broth 2.4–5.4 -OH; C=O; C=C 2.0–2.5 Geng et al.42
Mackerel Heating at 230°C in an oven 0.9–3.5 -OH; C=O; C-N 12 Li et al.43