Table 1.
Impact of routine vaccination on the incidence rates of the selected vaccine-preventable diseases
| Disease | Year of integration into EPI | Time perioda (years) | Change in incidence (%) (95% confidence interval)d | Change in incidence (%) (95% confidence interval)e |
|---|---|---|---|---|
| Measles | 1978 | 20 (1969–1988) | −79.66 (−87.97, −67.43) | −80.74 (−88.43, −69.60) |
| Pertussis | 1978 | 20 (1969–1988) | −82.6 (−89.26, −73.15) | −80.80 (−87.61, −71.41) |
| Diphtheria | 1978 | 20 (1969–1988) | −81.39 (−89.42, −69.3) | −81.29 (−89.39, −69.09) |
| Polio | 1978 | 20 (1969–1988) | −74.50 (−87.10, −53.53) | NA |
| Tuberculosisb | 1978 | NA | NA | NA |
| Hepatitis B | 2002 | 20 (1993–2012) | 109.30 (78.33, 146.39) | 1.72 (−73.75, 296.22) |
| Hepatitis B in newborns | 2002 | 20 (1993–2012) | 108.59 (55.75, 182.26) | −90.11 (−94.79, −82.95) |
| Mumpsc | 2007 | 8 (2004–2011) | 28.21 (0.19, 64.48) | NA |
| Rubellac | 2007 | 8 (2004–2011) | 82.49 (−9.50, 287.29) | NA |
| Hepatitis A | 2007 | 10 (2003–2012) | −54.21 (−66.18, −38.68) | −66.47 (−96.16, 68.24) |
| Meningococcal meningitis | 2007 | 10 (2003–2012) | −78.21 (−89.11, −60.13) | −76.25 (−98.12, 29.49) |
| Japanese encephalitis | 2007 | 10 (2003–2012) | −58.27 (−72.30, −38.50) | −65.26 (−95.86, 72.19) |
| Varicella | 2002 | 20 (1993–2012) | NA | 0.27 (−0.24, 0.79) |
| Varicella | 2004 | 20 (1995–2014) | NA | 0.74 (0.24, 1.25) |
| Varicella | 2007 | 20 (1998–2017) | NA | 1.4 (1.16, 1.64) |
| Paratyphoid fever | 2002 | 20 (1993–2012) | NA | 1.17 (0.53, 1.83) |
| Paratyphoid fever | 2004 | 20 (1995–2014) | NA | 2.14 (1.17, 3.12) |
| Paratyphoid fever | 2007 | 20 (1998–2017) | NA | 4.36 (2.29, 6.47) |
NA, no data available.
a
The number of years included in the regression is different for each disease and is based on the data availability and the year of integration into the EPI.
b
Tuberculosis: data available from 1997 onward.
c
Mumps and rubella: data available from 2004 onward.
d
Data from our reported system.
e
Data from GBD and estimate.