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. 2021 Mar 2;3:100047. doi: 10.1016/j.lanepe.2021.100047

Table 2.

Multimorbidity associated with individual conditions. Results are given as frequencies (row percent).

LTC Total LTC+1 other condition LTC+2 other conditions LTC+3 or more conditions
174,882 75,527 42,379 56,976
Cluster A
Anxiety 80,284 33,293 (41·5) 21,201 (26·4) 25,790 (32·1)
Depression 74,930 27,286 (36·4) 20,411 (27·2) 27,233 (36·3)
Cluster B
Heart failure 6788 352 (5·2) 580 (8·5) 5856 (86·3)
PAD 3576 176 (4·9) 320 (8·9) 3080 (86·1)
Osteoporosis 3634 213 (5·9) 365 (10) 3056 (84·1)
Atrial fibrillation 8178 723 (8·8) 927 (11·3) 6528 (79·8)
CHD 12,360 1121 (9·1) 1421 (11·5) 9818 (79·4)
CKD 14,726 1274 (8·7) 1853 (12·6) 11,599 (78·8)
Stroke/TIA 11,129 1145 (10·3) 1472 (13·2) 8512 (76·5)
Dementia 6342 507 (8) 812 (12·8) 5023 (79·2)
Cluster C
Osteoarthritis 30,083 4247 (14·1) 5264 (17·5) 20,572 (68·4)
Cancer 17,511 3556 (20·3) 3521 (20·1) 10,434 (59·6)
Chronic pain 90,302 20,934 (23·2) 23,784 (26·3) 45,584 (50·5)
Hypertension 59,295 13,270 (22·4) 12,200 (20·6) 33,825 (57)
Diabetes 30,121 6180 (20·5) 5614 (18·6) 18,327 (60·8)
Cluster D
Liver disease 3279 665 (20·3) 583 (17·8) 2031 (61·9)
Viral hepatitis 5302 1459 (27·5) 1116 (21) 2727 (51·4)
Cluster E
Alcohol dep. 15,233 3611 (23·7) 3375 (22·2) 8247 (54·1)
Substance dep. 9437 2036 (21·6) 1979 (21) 5422 (57·5)
HIV 4101 1398 (34·1) 1013 (24·7) 1690 (41·2)
No cluster
Asthma 40,299 15,775 (39.1) 9250 (23) 15,274 (37.9)
COPD 9276 849 (9.2) 1145 (12.3) 7282 (78.5)
Epilepsy 6091 1800 (29.6) 1284 (21.1) 3007 (49.4)
IBD 2247 1073 (47.8) 518 (23.1) 656 (29.2)
Learning disability 1875 580 (30.9) 474 (25.3) 821 (43.8)
Lupus 702 162 (23.1) 152 (21.7) 388 (55.3)
Severe mental health 9786 2324 (23.7) 2218 (22.7) 5244 (53.6)
Morbid obesity 14,762 3610 (24.5) 3004 (20.3) 8148 (55.2)
Multiple sclerosis 684 256 (37.4) 166 (24.3) 262 (38.3)
Parkinsons 1231 145 (11.8) 186 (15.1) 900 (73.1)
Rheumatoid arthritis 3444 747 (21.7) 684 (19.9) 2013 (58.4)
Sickle-Cell Anaemia 655 287 (43.8) 150 (22.9) 218 (33.3)

LTC = Long term condition, CHD=Coronary heart disease, CKD=chronic kidney disease, COPD= Chronic obstructive pulmonary disease, HIV= human immunodeficiency virus, IBD= Inflammatory bowel disease, PAD= Peripheral artery disease, TIA=Transient ischaemic attack.