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. 2021 Sep 20;8(5):ENEURO.0002-21.2021. doi: 10.1523/ENEURO.0002-21.2021

Table 2.

Properties of spontaneous burst firing in R-R, R-C, and R-H LNs

R-R/FM7 R-C/FM7 R-H/FM7
Burst frequency, Hz 22˚C: 0.70 ± 0.24 22˚C: 0.90 ± 0.26 22˚C: 0.70 ± 0.24
27˚C: 0.63 ± 0.26 27˚C: 0.57 ± 0.17 27˚C: 0.63 ± 0.26
22˚C: 0.57 ± 0.20 22˚C: 0.37 ± 0.16 22˚C: 0.57 ± 0.20
Action potential threshold, mV 22˚C: −37.77 ± 1.48 22˚C: −37.48 ± 1.83 22˚C: −38.00 ± 2.45
27˚C: −36.74 ± 1.36 27˚C: −37.06 ± 1.77 27˚C: −33.81 ± 3.10
22˚C: −36.79 ± 1.66 22˚C: −35.95 ± 2.08 22˚C: −36.17 ± 2.40
Action potential amplitude, mV 22˚C: 35.34 ± 2.35 22˚C: 32.27 ± 3.83 22˚C: 28.18 ± 5.16
27˚C: 28.29 ± 2.34 27˚C: 23.16 ± 3.19 27˚C: 23.33 ± 3.87
22˚C: 34.27 ± 3.81 22˚C: 28.52 ± 2.57 22˚C: 31.33 ± 4.16
Action potentials per burst 22˚C: 5.27 ± 0.39 22˚C: 5.24 ± 0.56 22˚C: 4.79 ± 0.35
27˚C: 5.46 ± 0.38 27˚C: 5.05 ± 0.56 27˚C: 4.34 ± 0.87
22˚C: 6.17 ± 0.50 22˚C: 5.31 ± 0.39 22˚C: 5.23 ± 0.49
Resting membrane potential, mV 22˚C: −57.1 ± 2.2 22˚C: −54.2 ± 2.0 22˚C: −54.0 ± 2.6
27˚C: −55.9 ± 1.8 27˚C: −52.1 ± 1.3 27˚C: −47.8 ± 3.2*
30˚C: −57.4 ± 2.4 30˚C: −58.3 ± 4.0 30˚C: −47.9 ± 1.9*
22˚C: −54.9 ± 3.2 22˚C: −49.5 ± 2.1 22˚C: −49.8 ± 1.8

Values are the mean ± SE at 22°C (during the 5 min preheating), “27°C” (during the minute of heating from 26°C to 29°C), and again at 22°C (during the 5 min postcooling).

*

R-H mutants have depolarized RMP at elevated temperatures compared with R-R controls; p < 0.05, two-way ANOVA.