Fig 5. Change in heart rate after antimalarial treatment for uncomplicated malaria in adolescents and adults (age ≥12 years).

Change in heart rate after treatment with the antimalarials artesunate-amodiaquine (ASAQ), chloroquine (CQ), dihydroartemisinin-piperaquine (DP), artemether-lumefantrine (AL), and pyronaridine-artesunate (PyAS) in adolescents and adults aged ≥12 years from a multivariable linear mixed effects regression model adjusting for sex, body temperature, and individual study/site/person effects. Lines indicate means with colour representing antimalarial treatment arm, shaded areas denote 95% confidence intervals, and dots are partial residuals.