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. 2021 Sep 7;18(9):e1003766. doi: 10.1371/journal.pmed.1003766

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© 2021 Chan et al

This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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Fig 6 — Change in heart rate after treatment with the antimalarials artesunate-amodiaquine (ASAQ), dihydroartemisinin-piperaquine (DP), artemether-lumefantrine (AL), and pyronaridine-artesunate (PyAS) in children aged <12 years from a multivariable linear mixed effects regression model adjusting for age, body temperature, and individual study/site/person effects. Lines indicate means with colour representing antimalarial treatment arm, shaded areas denote 95% confidence intervals, and dots are partial residuals.