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. Author manuscript; available in PMC: 2021 Sep 21.
Published in final edited form as: Sci Signal. 2020 Jul 7;13(639):eaax6313. doi: 10.1126/scisignal.aax6313

Fig. 2. WT AtFN3K is a beta-strand exchange disulfide-mediated dimer.

Fig. 2.

(A) Cartoon representation of the crystal structure of A. thaliana FN3K (AtFN3K) homodimer. The two disulfide bridges between two Cys32 and two Cys236 as well as the ADP molecules are shown as sticks. (B) Simulated annealing omit difference maps (Fo-Fc) calculated at 2.4 Å resolution and contoured at 4.5 rmsd. Maps were calculated after substituting both cysteines with alanine (top two panels) and removing the ADP molecule (bottom panel). (C) Top view of AtFN3K showing the beta-strand exchange.